As Our Network
Grows, So Does Hope

Aquadex Ultrafiltration Therapy is a cutting-edge solution that’s already helped many people regain a quality of life they thought they’d lost forever. Nuwellis is working around the clock with a growing network of physicians, scientists, and engineers to improve access to pioneering solutions to Fluid Overload.

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near you

Aquadex Ultrafiltration Therapy is available in hospitals in cities throughout the country. See all providers below.

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We’ve compiled answers to some of the most common questions we get. If you’d like to know more, you should consult your physician. In the meantime, you can download our brochure or contact us directly.

What is Fluid Overload?

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Fluid Overload, or hypervolemia, is a medical condition where there is too much fluid in the body. Excess fluid, primarily water and sodium, builds up throughout the body and bloodstream which may result in a range of symptoms and possibly hospitalization. Most of the time, the body will naturally dispose of this excess fluid through urination. However, with certain medical conditions, it may be necessary to provide the body with some assistance.

What are the symptoms of Fluid Overload?

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People with Fluid Overload commonly experience the following symptoms:

  • Weight gain
  • Excess fluid in lungs (pulmonary edema) causing difficulty breathing and/or coughing
  • Noticeable swelling in the arms, legs, or face (peripheral edema)
  • Swelling in the abdomen (ascites)
  • Extreme generalized edema/swelling of the skin (anasarca)
  • Poor wound healing
  • Fatigue

What causes Fluid Overload?

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Fluid Overload occurs when the body can no longer balance sodium and water levels. Excess sodium causes the body to retain more water. If the kidneys are unable to eliminate the excess salt and water, then Fluid Overload occurs.
Certain conditions and procedures make it difficult for the kidneys to keep the balance between sodium and water including:

  • Medical conditions like heart failure, heart disease, kidney disease, liver disease, cancer, and others
  • Procedures like heart surgery and other surgeries
  • Critical care and surgeries including severe infections (sepsis), burns, and trauma

How is Fluid Overload treated?

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The most common therapies for Fluid Overload are medications called diuretics. These are pills prescribed by your doctor to treat various conditions.

Ultrafiltration Therapy with Aquadex works like a mechanical diuretic, that gently and precisely removes excess water and sodium from your blood.

What are diuretics?

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Diuretics, also known as water pills, are drugs that can help your kidneys remove extra fluid from your vascular system. Though they can help treat Fluid Overload, they may not offer the precise fluid removal you may need and their effectiveness can be reduced over time.

“In total, there was 80 pounds of fluid removed from my body. I felt a new vigor to fight.” - Fernando

Contact us

If you or a loved one is suffering from heart failure induced Fluid Overload, and are interested in Aquadex Ultrafiltration Therapy, we’d love to hear from you.


See our patient
success stories

Fluid Overload and its underlying causes can be distressing and confusing, but there’s hope. We’re here to help you on your journey, and guide you every step of the way.


Learn about
our solutions

The Aquadex system gently and precisely removes excess fluid from the body. Simplified ultrafiltration with the Aquadex can be a life-changing alternative to diuretics and other, more complicated renal replacement technologies.