UNDERSTANDING
FLUID OVERLOAD

RESTORING FLUID BALANCE

If you or a loved one suffers from a condition that causes fluid overload, such as heart failure, Nuwellis offers the Aquadex Smartflow® System. This simplified ultrafiltration technology gently removes excess fluid and salt from the blood, restoring the body’s natural fluid balance.

WHAT IS FLUID OVERLOAD?

Fluid overload, or hypervolemia, is a medical condition where there is too much fluid in the body. Excess fluid, primarily salt and water, builds up throughout the body and bloodstream which may result in a range of symptoms and possibly hospitalization. Most of the time, the body will naturally dispose of this excess fluid through urination. However, with certain medical conditions, it may be necessary to provide the body with some assistance.

WHAT ARE THE SYMPTOMS OF FLUID OVERLOAD?

Fluid overload is a serious condition that puts stress on organs and tissues. If left untreated, fluid overload can cause several complications, some of which are life-threatening.

People with fluid overload commonly experience the following symptoms:

  • Weight gain
  • Excess fluid in lungs (pulmonary edema) causing difficulty breathing and/or coughing
  • Noticeable swelling in the arms, legs, or face (peripheral edema)
  • Swelling in the abdomen (ascites)
  • Extreme generalized edema/swelling of the skin (anasacra)
  • Poor wound healing
  • Fatigue

WHAT CAUSES FLUID OVERLOAD?

Fluid overload occurs when the body can no longer balance sodium and water levels. Excess sodium causes the body to retain more water. If the kidneys are unable to eliminate the excess salt and water, then fluid overload occurs. Certain conditions and procedures make it difficult for the kidneys to keep the balance between sodium and water including:

Medical Conditions

Heart failure, nephrotic syndrome (kidney disorder causing the body to leak too much protein into the urine), and liver or kidney damage/failure.

Surgical Procedures

Increased IV fluid or sodium intake during certain surgical procedures like coronary artery bypass graft (CABG), valve repair/replacement, atrial fibrillation ablation, and other procedures.

Critical Care

Fluid remobilization after treatment for severe infections (sepsis), burns, or trauma.

HOW IS FLUID OVERLOAD TREATED?

Treatment of fluid overload differs from person to person depending on the cause of the condition. For most people, taking medications called diuretics (water pills) will help remove excess fluid in the body. Patients with certain underlying conditions either do not adequately respond to diuretics or develop resistance to therapy over time.

Simplified ultrafiltration therapy is an option for treating fluid overload in people where diuretics have failed.

IS SIMPLIFIED ULTRAFILTRATION RIGHT FOR ME OR MY FAMILY MEMBER?

Simplified ultrafiltration therapy using the Aquadex SmartFlow System is a method of removing excess fluid, mainly water and salt, from your body when conventional approaches are not working. A physician prescription is required to receive this treatment.

Your clinician may recommend simplified ultrafiltration therapy for:

Adults

  • “Water weight” gain of 10 pounds or more.
  • Failure of diuretics or medical treatment to adequately reduce water weight.
  • Frequent hospitalizations for fluid overload.

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Pediatrics

In critically ill pediatric patients, managing fluid balance is crucial in reducing the risk of morbidity and mortality. Simplified ultrafiltration using the Aquadex SmartFlow System is indicated to treat fluid overload in pediatric patients ≥ 20KG.

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Simplified ultrafiltration with the Aquadex SmartFlow System

If symptoms of fluid overload have prevented you or a loved one from enjoying everyday activities, simplified ultrafiltration may be able to help.

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